Beilstein J. Org. Chem.2019,15, 695–702, doi:10.3762/bjoc.15.64
and Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China 10.3762/bjoc.15.64 Abstract A detailed chemical investigation of the South China Sea soft corals Clavulariaviridis and Lemnalia flava yielded four
extensive spectroscopic analysis and by comparison with the previously reported analogues. In a bioassay, compounds 1, 2 and 4 exhibited interesting inhibitory activities in vitro against PTP1B and NF-κB.
Keywords: Clavulariaviridis; Lemnalia flava; NF-κB; PTP1B; sesquiterpenoid; soft coral, terpenes
, cytotoxic, to anti-inflammatory properties [10].
In the framework of our ongoing research for the bioactive metabolites from South China Sea soft corals [11][12], we made the collection of the title samples Clavulariaviridis and Lemnalia flava off the Xisha Islands, Hainan Province, China. The chemical